Friday, April 27, 2012

Base Pairing

Nucleotide - Nucleoside + phosphate group.

Adenine - thymine (uracil in RNA) - 2 bonds
Guanine - Cytosine - 3 bonds

Purines - A,G - Pure As Gold

Wobble effect - Multiple codons for same amino acid. These multiple codons mostly differ only in the third nucleotide. So,  a substitution on the third nucleotide will not cause any harm.

DNA is
Highly polar
hydrophilic
has major and minor groove - major groove is binding site for proteins


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